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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
8.18
Human Site:
T439
Identified Species:
13.85
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
T439
N
L
P
Q
S
P
G
T
D
Q
H
D
R
K
C
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
T439
N
L
P
Q
S
P
G
T
D
Q
H
D
R
K
C
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
E429
S
S
A
S
V
P
V
E
I
E
N
L
P
Q
N
Dog
Lupus familis
XP_532028
914
101864
S521
P
S
P
G
L
S
S
S
D
R
L
P
F
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
E439
L
P
Q
T
S
A
T
E
Q
H
D
R
K
C
L
Rat
Rattus norvegicus
Q5FVG2
731
81700
D439
L
P
Q
N
S
A
A
D
Q
H
D
R
K
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
L439
D
S
S
V
K
L
K
L
L
E
T
E
N
S
F
Chicken
Gallus gallus
XP_422083
502
57358
P213
K
E
C
R
G
Q
T
P
A
Q
A
E
T
N
Y
Frog
Xenopus laevis
NP_001080234
498
57093
R209
L
G
K
W
K
D
F
R
G
Q
T
P
A
E
A
Zebra Danio
Brachydanio rerio
O57457
619
70690
G330
G
K
T
A
M
Q
I
G
R
E
S
T
E
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
N454
P
T
P
N
N
D
N
N
N
D
A
F
D
S
L
Honey Bee
Apis mellifera
XP_623974
809
90976
A519
D
S
L
L
K
S
L
A
K
D
Q
Q
P
L
E
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
S600
S
P
P
R
S
K
R
S
P
Q
S
N
K
S
S
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
P434
A
N
A
T
V
H
S
P
T
V
T
L
P
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
0
6.6
6.6
0
N.A.
6.6
0
20
0
P-Site Similarity:
100
100
33.3
26.6
N.A.
13.3
20
N.A.
20
20
13.3
6.6
N.A.
20
6.6
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
8
0
15
8
8
8
0
15
0
8
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
15
% C
% Asp:
15
0
0
0
0
15
0
8
22
15
15
15
8
0
0
% D
% Glu:
0
8
0
0
0
0
0
15
0
22
0
15
8
8
15
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
8
% F
% Gly:
8
8
0
8
8
0
15
8
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
15
15
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% I
% Lys:
8
8
8
0
22
8
8
0
8
0
0
0
22
15
0
% K
% Leu:
22
15
8
8
8
8
8
8
8
0
8
15
0
8
29
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
8
0
15
8
0
8
8
8
0
8
8
8
8
8
% N
% Pro:
15
22
36
0
0
22
0
15
8
0
0
15
22
0
0
% P
% Gln:
0
0
15
15
0
15
0
0
15
36
8
8
0
8
0
% Q
% Arg:
0
0
0
15
0
0
8
8
8
8
0
15
15
8
0
% R
% Ser:
15
29
8
8
36
15
15
15
0
0
15
0
0
22
8
% S
% Thr:
0
8
8
15
0
0
15
15
8
0
22
8
8
8
0
% T
% Val:
0
0
0
8
15
0
8
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _